Abstract KRAS is the most common mutated oncogenes in caruso rhodiola colorectal cancer (CRC), yet effective therapeutic strategies for targeting multiple KRAS mutations remained challenging.The prolonged protein stability of KRAS mutants contribute to their robust tumor-promoting effects, but the underlying mechanism is elusive.Herein by screening
Hemangiomas are rare vascular benign tumors.Frequency of hemangiomas in genital region is quite uncommon with less credible occurrence in adult valhalla axys population.These are classified into capillary, cavernous, arteriovenous, venous and mixed sub-types.These patients have a poor prognosis and may require surgical intervention.We present case
Protein kinase ALK3/BMPR1A mediates bone morphogenetic protein (BMP) signalling g35 coupe fender through phosphorylation and activation of SMADs 1/5/8.SMAD6, a transcriptional target of BMP, negatively regulates the BMP pathway by recruiting E3 ubiquitin ligases and targeting ALK3 for ubiquitin-mediated degradation.Here, we identify a deubiquitylat
The study included 100 samples collected from different locations of the homes were located in the area of Ali ribavirin coupon Saleh in Baghdad 6 species were isolated from fungi and the most common genus or species of fungi isolated were Aspergillus fumigatus by frequency ratio of 25.84%, and occurrence ratio of 23%, Penicilium by frequency ratio